Individuals with breast most cancers have a better threat of blood clots like a deep vein thrombosis (DVT). Their threat is higher because of the cancer itself and several treatments for breast most cancers. In case the cancer has spread to other parts of the body (secondary breast cancer), this also boosts the threat.

larotrectinib will increase the amount or outcome of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.

Embryo-Fetal Toxicity Advise Expecting Gals and females of reproductive likely that publicity in the course of pregnancy or within just one month previous to conception may end up in fetal hurt.

Some people gain from switching to another hormone therapy. As an example, it might be achievable to modify to a different aromatase inhibitor to determine When your ache enhances, or some individuals may very well be supplied the drug tamoxifen in its place.

Girls who have the ability to grow to be Expecting need to use efficient start Regulate (contraceptive) all through treatment method with AROMASIN and for 1 thirty day period immediately after your final dose of AROMASIN. Notify your medical professional instantly in case you grow to be pregnant or Imagine here you may well be Expecting.

Even though ache relievers which include acetaminophen and NSAIDs may help reduce the pain, NSAIDs by themselves have their Unwanted side effects and really should not be taken extended-time period Unless of course less than a doctor's assistance. Carry on looking at

People getting exemestane that has a strong CYP450 3A4 inducer which include rifampin or phenytoin: fifty mg the moment daily following a meal

oxcarbazepine will lower the level or result of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. For patients receiving exemestane having a potent CYP3A4 inducer the advised dose of exemestane is 50 mg day-to-day after a meal.

Indicated for treatment of Highly developed breast most cancers in postmenopausal Ladies whose sickness has progressed subsequent tamoxifen therapy

The following adverse reactions happen to be discovered through put up approval utilization of AROMASIN. Mainly because these reactions are documented voluntarily from the population of unsure size, It is far from constantly attainable to reliably estimate their frequency or set up a causal relationship to drug exposure.

Coadministration of encorafenib with sensitive CYP3A4 substrates may lead to improved toxicity or lowered efficacy of these agents.

estrogens conjugated artificial decreases results of exemestane by pharmacodynamic antagonism. Use Caution/Check. Estrogens or estrogen-containing goods, like combined oral contraceptives, should not be offered concomitantly with exemestane; these medication could interfere While using the pharmacologic motion and efficacy of exemestane.

You may need to maintain getting get this medicine for up to five years. Stick to your medical doctor's Guidelines. This medication may not operate also if you take it along with hormone substitute medication.

Look at together with your medical doctor right away if any of the subsequent side effects come about whilst getting exemestane: